Mental health and substance use disorders deaths in United States of America

United States of America: Mental health and substance use disorders deaths was 128,367 deaths in 2021. ◆ Volatile

Latest (2021)
128,367 deaths
Change on year
up 14.9%
World rank
1st
of 194 countries
All-time high
128,367 deaths
in 2021
All-time low
22,130 deaths
in 2000
Years of data
22
2000–2021

Mental health and substance use disorders deaths in United States of America, 2000–2021

25.0k50.0k75.0k100.0k125.0k2000201020212000: 22.1k deaths2001: 23.9k deaths2002: 27.7k deaths2003: 30.1k deaths2004: 32.0k deaths2005: 35.1k deaths2006: 39.3k deaths2007: 39.3k deaths2008: 40.3k deaths2009: 40.9k deaths2010: 42.5k deaths2011: 46.2k deaths2012: 47.0k deaths2013: 50.1k deaths2014: 53.9k deaths2015: 60.6k deaths2016: 73.0k deaths2017: 80.2k deaths2018: 78.2k deaths2019: 83.0k deaths2020: 111.7k deaths2021: 128.4k deaths

Source: World Health Organization (2024) – with major processing by Our World in Data. Measured in deaths.

Analysis

United States of America recorded 128,367 deaths for mental health and substance use disorders deaths in 2021. That is the highest value across all 22 years on record.

The figure is up 14.9% on the previous year and up 178.0% over ten years.

Over the whole period, mental health and substance use disorders deaths in United States of America peaked at 128,367 deaths in 2021 and was at its lowest, 22,130 deaths, in 2000.

That places United States of America 1st out of 194 countries with data for 2021, putting it in the top 10%.

The series is highly variable year to year, so single readings are best treated with caution.

Mental health and substance use disorders deaths in United States of America, year by year

Annual values for Mental health and substance use disorders deaths in United States of America, 2000 to 2021.
Year deaths Change
2000 22,130 deaths
2001 23,860 deaths +7.8%
2002 27,676 deaths +16.0%
2003 30,100 deaths +8.8%
2004 31,954 deaths +6.2%
2005 35,132 deaths +9.9%
2006 39,348 deaths +12.0%
2007 39,251 deaths -0.2%
2008 40,296 deaths +2.7%
2009 40,927 deaths +1.6%
2010 42,518 deaths +3.9%
2011 46,179 deaths +8.6%
2012 46,956 deaths +1.7%
2013 50,085 deaths +6.7%
2014 53,853 deaths +7.5%
2015 60,616 deaths +12.6%
2016 72,978 deaths +20.4%
2017 80,192 deaths +9.9%
2018 78,204 deaths -2.5%
2019 83,025 deaths +6.2%
2020 111,734 deaths +34.6%
2021 128,367 deaths +14.9%

Averages by decade

DecadeAverage LowestHighest Years
2000s 33,068 deaths 22,130 deaths 40,927 deaths 10
2010s 61,461 deaths 42,518 deaths 83,025 deaths 10
2020s 120,050 deaths 111,734 deaths 128,367 deaths 2

Countries ranked near United States of America

  1. 2 China 29,710 deaths compare
  2. 3 India 29,217 deaths compare
  3. 4 Russian Federation 25,668 deaths compare

See the full ranking of 194 places →

More health data for United States of America

All data for United States of America →

Frequently asked questions

What is mental health and substance use disorders deaths in United States of America?
Mental health and substance use disorders deaths in United States of America was 128,367 deaths in 2021, according to World Health Organization (2024) – with major processing by Our World in Data.
What is the highest mental health and substance use disorders deaths recorded in United States of America?
The highest recorded value was 128,367 deaths in 2021.
What is the lowest mental health and substance use disorders deaths recorded in United States of America?
The lowest recorded value was 22,130 deaths in 2000.
How does United States of America rank for mental health and substance use disorders deaths?
United States of America ranks 1st out of 194 countries with data for 2021.
Is mental health and substance use disorders deaths rising or falling in United States of America?
Over the last ten years it is up 178.0%. The long-run trend across the full record is volatile.
Where does this United States of America data come from?
The figures come from World Health Organization (2024) – with major processing by Our World in Data, published as part of Mental health and substance use disorders deaths. Statizoid updates them automatically from the source API.

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Mental health and substance use disorders deaths in United States of America. Statizoid, drawing on World Health Organization (2024) – with major processing by Our World in Data. Retrieved 11 September 2026, from https://health.statizoid.com/stat/deaths-from-mental-health-and-substance-use-disorders-who/united-states/

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About this data

Indicator
Mental health and substance use disorders deaths
Unit
deaths
Source
World Health Organization (2024) – with major processing by Our World in Data
Licence
CC BY 4.0 (Our World in Data)
Coverage
194 places, 4,268 data points, 2000–2021
Last refreshed

Estimated number of deaths from mental and substance use disorders in both sexes.