Drug use disorder deaths in United States

United States: Drug use disorder deaths was 106,981 deaths in 2021. ◆ Volatile

Latest (2021)
106,981 deaths
Change on year
up 16.6%
World rank
1st
of 194 countries
All-time high
106,981 deaths
in 2021
All-time low
14,203 deaths
in 2000
Years of data
22
2000–2021

Drug use disorder deaths in United States, 2000–2021

20.0k40.0k60.0k80.0k100.0k2000201020212000: 14.2k deaths2001: 15.6k deaths2002: 19.1k deaths2003: 21.3k deaths2004: 22.9k deaths2005: 25.9k deaths2006: 30.0k deaths2007: 30.3k deaths2008: 30.9k deaths2009: 31.5k deaths2010: 32.6k deaths2011: 35.9k deaths2012: 36.1k deaths2013: 38.8k deaths2014: 42.1k deaths2015: 48.1k deaths2016: 59.6k deaths2017: 66.3k deaths2018: 63.8k deaths2019: 67.7k deaths2020: 91.7k deaths2021: 107.0k deaths

Source: World Health Organization (2024) – with major processing by Our World in Data. Measured in deaths.

Analysis

United States recorded 106,981 deaths for drug use disorder deaths in 2021. That is the highest value across all 22 years on record.

Compared with earlier readings it is up 16.6% on the previous year and up 198.2% over ten years.

Over the whole period, drug use disorder deaths in United States peaked at 106,981 deaths in 2021 and was at its lowest, 14,203 deaths, in 2000.

United States ranks 1st of 194 countries on this measure, in the top 10%.

The series is highly variable year to year, so single readings are best treated with caution.

Drug use disorder deaths in United States, year by year

Annual values for Drug use disorder deaths in United States, 2000 to 2021.
Year deaths Change
2000 14,203 deaths
2001 15,583 deaths +9.7%
2002 19,101 deaths +22.6%
2003 21,294 deaths +11.5%
2004 22,929 deaths +7.7%
2005 25,912 deaths +13.0%
2006 29,969 deaths +15.7%
2007 30,340 deaths +1.2%
2008 30,856 deaths +1.7%
2009 31,541 deaths +2.2%
2010 32,564 deaths +3.2%
2011 35,874 deaths +10.2%
2012 36,146 deaths +0.8%
2013 38,797 deaths +7.3%
2014 42,125 deaths +8.6%
2015 48,100 deaths +14.2%
2016 59,572 deaths +23.9%
2017 66,260 deaths +11.2%
2018 63,777 deaths -3.7%
2019 67,690 deaths +6.1%
2020 91,741 deaths +35.5%
2021 106,981 deaths +16.6%

Averages by decade

DecadeAverage LowestHighest Years
2000s 24,173 deaths 14,203 deaths 31,541 deaths 10
2010s 49,090 deaths 32,564 deaths 67,690 deaths 10
2020s 99,361 deaths 91,741 deaths 106,981 deaths 2

Countries ranked near United States

  1. 2 China 11,246 deaths compare
  2. 3 India 8,450 deaths compare
  3. 4 Canada 7,333 deaths compare

See the full ranking of 194 places →

More health data for United States

All data for United States →

Frequently asked questions

What is drug use disorder deaths in United States?
Drug use disorder deaths in United States was 106,981 deaths in 2021, according to World Health Organization (2024) – with major processing by Our World in Data.
What is the highest drug use disorder deaths recorded in United States?
The highest recorded value was 106,981 deaths in 2021.
What is the lowest drug use disorder deaths recorded in United States?
The lowest recorded value was 14,203 deaths in 2000.
How does United States rank for drug use disorder deaths?
United States ranks 1st out of 194 countries with data for 2021.
Is drug use disorder deaths rising or falling in United States?
Over the last ten years it is up 198.2%. The long-run trend across the full record is volatile.
Where does this United States data come from?
The figures come from World Health Organization (2024) – with major processing by Our World in Data, published as part of Drug use disorder deaths. Statizoid updates them automatically from the source API.

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Drug use disorder deaths in United States. Statizoid, drawing on World Health Organization (2024) – with major processing by Our World in Data. Retrieved 01 September 2026, from https://health.statizoid.com/stat/deaths-from-drug-use-disorders-ghe/united-states/

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About this data

Indicator
Drug use disorder deaths
Unit
deaths
Source
World Health Organization (2024) – with major processing by Our World in Data
Licence
CC BY 4.0 (Our World in Data)
Coverage
194 places, 4,268 data points, 2000–2021
Last refreshed

Estimated number of deaths from drug use disorders in both sexes.